Cancer immunology is a stream of immunology that studies communications between the immune system and cancer cells (also called tumors or malignancies). It is a field of research that intent to discover cancer immunotherapies to treat and decelerate evolution of the disease. The human immune system mounts natural endogenous response to foreign cells. The gamut of genetics and epigenetics changes occurring in tumors provides diverse set of antigenic repertoire that host’s immune system can exploit to distinguish tumour versus their normal healthy counterparts.